Explore cancer metabolic subtypes, analyze enzyme-survival associations, predict HCC subtypes, and infer enzyme activity for your own samples
A streamlined workflow from data selection to result download
Choose from 33 TCGA cancer types with pre-computed metabolic enzyme activity
Set parameters for clustering, survival analysis, or enzyme activity inference
Execute the analysis and explore interactive visualizations and results
Export figures, tables, and full activity matrices for your research
Comprehensive metabolic enzyme activity across the TCGA pan-cancer atlas
If you use iMetAct in your research, please cite:
Wang, B., Huang, C., Liu, X., Liu, Z., Zhang, Y., Zhao, W., Xu, Q., Ho, P. C., & Xiao, Z. (2025). iMetAct: An integrated systematic inference of metabolic activity for dissecting tumor metabolic preference and tumor-immune microenvironment. Cell Reports, 44(3), 115375.
https://doi.org/10.1016/j.celrep.2025.115375