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iMetActv2.0
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iMetAct v2.0 — Inference of Metabolic Enzyme ActivityData sourced from TCGA Research Network. For research use only.
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Data Download

Data Repository

Download pre-computed metabolic enzyme activity matrices, GSVA pathway scores, and NMF cluster assignments for each cancer type.

iMetAct R Package

Run the complete iMetAct workflow locally in R. Infer metabolic enzyme activity from gene expression data using the iMetAct method, perform NMF-based cancer stratification, survival analysis, and subtype prediction — all from your R console.

github.com/bigbinb/iMetAct

Enzyme Activity (KEGG)

iMetAct-inferred metabolic enzyme activity scores from KEGG-defined metabolic genes.

Pathway Activity (GSVA)

GSVA pathway enrichment scores for Reactome metabolic pathways.

Cluster Assignments

NMF cluster sample assignments. Select cancer, database, method, and cluster number (k).